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These findings suggest direct toxic effects of chemotherapy on the cardiovascular system.

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One previous study reported subacute deterioration of diastolic function, assessed with echocardiography 10 months after cisplatin-based chemotherapy (Altena et al, 2009).

Our investigation included a 230-ft-long trench to “clear” the site regarding the potential presence of the Crosley fault.

We also advised the owner on the issue of slope stability.

The aforementioned indirect risk factors are all independently associated with a higher risk of cardiovascular disease and may contribute to the overall increased risk of cardiovascular complications after treatment with cisplatin-based chemotherapy.

The increased risk of cardiovascular disease in cured TC patients after cisplatin-based chemotherapy is probably a combination of direct and indirect effects of chemotherapy (Einhorn, 1997; Devaraj et al, 2011).

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